Hybrid stars with the color dielectric and the MIT bag models

We study the hadron-quark phase transition in the interior of neutron stars (NS). For the hadronic sector, we use a microscopic equation of state (EOS) involving nucleons and hyperons derived within the Brueckner-Bethe-Goldstone many-body theory, with realistic two-body and three-body forces. For the description of quark matter, we employ both the MIT bag model with a density dependent bag constant, and the color dielectric model. We calculate the structure of NS interiors with the EOS comprising both phases, and we find that the NS maximum masses are never larger than 1.7 solar masses, no matter the model chosen for describing the pure quark phase.Comment: 11 pages, 5 figures, submitted to Phys. Rev.

Structural elements of coordination mechanisms in collaborative planning processes and their assessment through maturity models: Application to a ceramic tile company

Maturity is defined as a measure to evaluate the capabilities of an organization in regards to a certain discipline. The Collaborative Planning Process is a very complex process and Coordination mechanisms are especially relevant in this field to align the plans of the supply chain members. The objective of this paper is to develop a maturity model and a methodology to perform assessment for the Structural Elements of Coordination Mechanisms in the Collaborative Planning Process. Structural elements are specified in order to characterize coordination mechanisms in a collaborative planning context and they have been defined as key areas to be assessed by the maturity model. The identified structural elements are: number of decision-makers, collaboration level, interdependence relationships nature, interdepen-dence relationships type, number of coordination mechanisms, information exchanged, information processing, decision sequence characteristics and stopping criteria. Structural elements are assessed using the scheme of five levels: Initial, Repeatable, Defined, Managed and Optimized. This proposal has been applied to a ceramic tile company and the results are also reported.Cuenca, L.; Boza Garcia, A.; Alemany Díaz, MDM.; Trienekens, JJ. (2013). Structural elements of coordination mechanisms in collaborative planning processes and their assessment through maturity models: Application to a ceramic tile company. Computers in Industry. 64(8):898-911. doi:10.1016/j.compind.2013.06.019S89891164

Modélisation des micropolluants en bioréacteurs à membranes: calage du modèle, optimisation du procédé

International audienceMicropollutants are a major concern for aquatic organisms and human health. Membrane bioreactors (MBRs) are an efficient wastewater treatment and water reuse solution, but their micropollutant removal performances are still not fully determined. Modeling micropollutant behavior in MBRs could help better understand and optimize the removal process. Here we provide detailed explanation on a model of micropollutant removal in MBRs that predicts biodegradation and sorption rates. Parameters were calibrated following an iterative two-step procedure developed in this work and using data from two full-scale plants. The calibrated set of parameters was then used (i) to determine the influence of MBR operating conditions such as the duration of aerobic time and the sludge concentration in bioreactor, on micropollutant removal, and (ii) to better understand micropollutant behavior and removal performances in MBRs in response to sudden changes in operating conditions (rain event, F:M ratio). These predictive simulations showed that increasing sludge concentration in bioreactor can decrease effluent concentrations of most of the micropollutants studied by up to 15%, and increasing the duration of aerobic time decreases effluent concentrations of few organic micropollutants tested by up to 15%. Rain events and F:M ratio can increase effluent concentrations of six out of nine micropollutants tested by more than 15%

Modélisation du devenir des micropolluants dans les stations d'épuration

National audienc

C, N, P concentrations and requirements of flowering <i>Posidonia oceanica</i> shoots

The carbon, nitrogen and phosphorus contents in flowering and nonflowering shoots were compared after an important flowering event occurred in the Posidonia meadow of the Bay of Calvi. The flower formation caused a significant increase of C and a significant decrease of N concentrations in intermediate and adult leaves. Minimum daily requirements in mg shoot-1 day-1 of 3.4 and 4.8 of C, 0.09 and 0.09 N, 0.01 and 0.02 of P respectively for nonflowering and flowering shoots were calculated. It shows that additional quantities of C and P are required for the inflorescence elaboration. The unchanged quantity of N required by the shoot for the inflorescence elaboration and the significant modification of N concentration in intermediate and adult leaves suggests that N is limited in the environment and that an efficient resorption of N occurs from leaves to ensure the inflorescence formation

Septic shock like syndrome observed with TNF given for isolated limb perfusion

SCOPUS: cp.jinfo:eu-repo/semantics/publishe

Isolation limb perfusion with tumor necrosis factor alpha and chemotherapy for advanced extremity soft tissue sarcomas.

The unique property of high dose recombinant tumor necrosis factor alpha (rTNF alpha) is to activate and selectively destroy the tumor-associated microvasculature. For the systemic application of rTNF alpha it has been shown that the maximum tolerated dose (MTD) is 10 times less than the effective dose in animals. The main toxicity corresponds to systemic inflammatory response syndrome with a decrease in vascular resistance and hypotension. We found that it is possible to administer rTNF alpha at 10 times the MTD in an isolated limb perfusion (ILP) system with heart-lung machine, for locally advanced extremity soft tissue sarcomas. One hundred forty patients received an ILP with high-dose TNF alpha. In 55 patients treated with the combination of high-dose rTNF alpha + interferon-gamma + melphalan an overall objective response rate of 87% with 36% complete responses was observed; it was 81% and 28%, respectively, in a group treated with TNF alpha and melphalan (n = 85). Angiographic and immunohistological studies showed the selective and early damage of the sarcoma-associated microvasculature preceded by the upregulation of adhesion molecules and intratumoral leak of von Willebrand factor. Tumor invasion by platelets and, in some cases, by polymorphonuclear cells, appeared within hours after the application of rTNFa long before the lysis of the tumor. Thus, ILP with high-dose TNF alpha and chemotherapy seems to act through a dual targeting: TNF hits the tumor associated vasculature, and chemotherapy attacks the tumor cells. Therefore, ILP with TNF is a new option in the management of locally advanced soft tissue sarcoma of the extremities